Temporary — will retry
SMTP 451 4.7.500
access denied, try again later (Microsoft 365)
SMTP 451 4.7.500 to 4.7.699 (shown with an ASxxx tag) is Microsoft 365 temporarily throttling mail from your IP. Microsoft calls it a form of greylisting: the IP's volume rose sharply compared with its history, so mail is deferred while it builds a record. It is temporary and usually clears in a few days.
How it appears
451 4.7.500 Server busy. Please try again later from [203.0.113.5]. (AS843)
What causes it
- A sudden increase in volume from an IP Microsoft has little history for.
- A new sending IP or server sending at full volume from day one.
- Mail being sent from the tenant's onmicrosoft.com domain.
How to fix it
In order — try the first one first.
- Let your server keep retrying. Deferred mail is normally accepted as the IP builds history.
- Ramp volume up gradually on new IPs.
- Send from your own domain, not onmicrosoft.com.
- Check that SPF, DKIM and DMARC pass, so reputation builds on an authenticated identity.
Common questions
- What does SMTP 451 4.7.500 mean?
- SMTP 451 4.7.500 to 4.7.699 (shown with an ASxxx tag) is Microsoft 365 temporarily throttling mail from your IP. Microsoft calls it a form of greylisting: the IP's volume rose sharply compared with its history, so mail is deferred while it builds a record. It is temporary and usually clears in a few days.
- Should I retry a 451 4.7.500 error?
- Yes, and your sending server does it automatically. 451 is a temporary deferral, and legitimate mail usually arrives on a retry within minutes or hours. Only investigate if it persists across many retries.
- How do I fix SMTP 451 4.7.500?
- Let your server keep retrying. Deferred mail is normally accepted as the IP builds history.
Other 451 replies
Last reviewed 2026-09-11